Infectious Disease Antibodies

Monoclonal anti-HIV p24

Cat.# 3H24

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Cat.#

3H24
Recombinant MAbs

GA32, GA34, GA38, GA39
Recombinant monoclonal antibody expressed in a mammalian cell line. Full-size IgG sequence derived from rabbit B cells.

GA54
Recombinant chimeric antibody expressed in a mammalian cell line. Composed of original wild typevariable domains of rat derived MAb and human IgG1 constant domains.
MAbs in vitro

GA12, GA15, GA18
Mouse monoclonal antibody produced in bioreactor. Hybridoma clone derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice.
MAbs in vivo

GA17
Mouse monoclonal antibody produced in ascites. Hybridoma clone derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice.
Immunogen:

Recombinant HIV p24
Specificity:

HIV-1 p24 (group M), cross-reacts with HIV-1 p24 (group O) and HIV-2 p26
MAb isotypes:

IgG for GA32, GA34, GA38, GA39
IgG1 for GA12, GA15, GA17, GA18, GA54
Applications:

All MAbs can be used in ELISA.

*All pairs can detect WHO HIV-1 p24 international standard material (NIBSC code: 90/636), recombinant HIV-1 p24 antigen, and recombinant HIV-2 p26 antigen.
Purification:

Protein A chromatography
Presentation:

PBS, pH 7.4, 0.09 % sodium azide (NaN3 ) for GA32, GA34, GA38, GA39, GA54

50 mM sodium citrate, 150 mM NaCl, pH 6.0, 0.09 % sodium azide (NaN3) for GA12, GA15, GA17, GA18
Storage:

+4 °C (+2 … +8 °C allowed)
Material safety note:

This product is sold for research or further manufacturing use only. Standard Laboratory Practices should be followed when handling this material.

Product contains sodium azide as a preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

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Cat.# 3H24

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